Is Colchicine safe for breastfeeding mothers?

Doctor's Answer

As Dr Jasmine mentioned, there’s not much literature available regarding the use of colchicine in breastfeeding.

The most recent, albeit small scale study done in 2015 with 37 women who breastfed while on colchicine showed that there was no increase in harmful long-term outcomes.

Other studies have shown that even though colchicine is secreted into breastmilk (with the highest milk levels occurring 2 to 4 hours after taking your medication), there has not been any published literature (to my knowledge) about harmful effects on infants who were breastfed while their moms were on colchicine.

The general guideline with the use of colchicine in breastfeeding women is that you and your specialist should continue to observe your infant for adverse effects.

Moving forward, you should definitely take up these concerns regarding the use of colchicine and breastfeeding with the specialist managing your oral lichen planus, as he will be able to advise you on the best course of action regarding continuing, or switching the medication.

At the end of the day, the use of any medication is always a matter of risks (harmful side effects) versus benefits. Your specialist may have chosen to continue you on colchicine as your oral lichen planus may have responded best to this medication, as opposed to others.

It would be remiss for doctors on Human to suggest to you an alternative medication for your specialist to switch you on to, as we will not know what medications he may have already tried you on previously, or how severe your lichen planus is, etc. etc.

Cheers

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