The injection in dupixent is usually given as 2 weekly injections. So, it is given as a subcutaneous injection, at the start usually, there is a loading dose of two injections and subsequent every 2 weeks it's given.
In terms of the clinical trials, we do see a group of patients maybe 30-40% who are very fast respondents. The moment you inject, in 1-2 weeks the itch is completely gone and within a month you see the skin settling very well.
Usually, by 3 months we know whether or not the drug is working well for you and if your skin has done well, we will know you are a good respondent. If after 3 months of using the medication, we do not see the response then you might be one of those who might not respond well to the injection.
But generally, it is a 2-weekly injection, the speed of response as I said can vary in an individual but for some people, it can be quite fast.
