How can I minimise the risks associated with taking oral steroids like prednisolone?

Doctor's Answers 1

Oral steriods such as prednisolone have strong anti-inflammatory properties and should only be taken under close medical supervision.

Serious side effects may occur if not used with caution. Usually only short courses of a few weeks are given and in most patients will not cause any serious problems.

If oral steroids are used at doses that are too high, or for too long a period of time, patients may:

  • develop weight gain
  • moon face
  • increased hairgrowth
  • muscle weakness
  • hypertension
  • diabetes
  • cataracts etc.

Your doctor will make sure you have no underlying conditions that make it unsafe for you to take prednisolone before starting you on the medicine.

They will keep a close eye on you when you are taking the prednisolone to ensure that you have no side effects, and that your blood pressure and blood sugar are normal.

Most patients are gradually tapered off the dose to prevent a rebound of your original condition.

Seeing a trusted doctor whilst taking the prednisolone would be the best way to minimise any associated risks. Hope this helps.

Best regards

Dr Stephanie Ho, Dermatologist

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Sorry to hear that your child has developed hives after an episode of viral illness. I agree with Dr Colin Theng that a viral infection is most likely the trigger for this episode and antihistamines such as cetirizine would be the mainstay of treatment. I would usually optimise the dose of antihistamines for good control. If the maximum dose is still not able to control your child's hives, then a course of prednisolone may need to be considered. These medicines will help to switch off the activity of mast cells which have gone into overdrive, causing the appearance of hives.

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