Does a low dosage isotretinoin course which falls below the recommended total cumulative dosage increase the chance of a relapse?

Doctor's Answer

The right approach really depends on your social needs and whether the side effects have been horrible.

The conventional method is to achieve a cumulated dose (usually 120mg/kg) and this usually does result in a acne-reduced state for a few years. I have taken 2 courses before which helped but in the end, I self-adjusted and now I take the very occasional dose (maybe once a fortnight) and it works for me.

But yes if the dose is TOO LOW, the risk of relapse is definitely higher, but a high dose comes with higher risks of side effects. My personal practice for my patients is to start higher but after that drag the treatment duration for a while (with a low dose). Seems to work quite well, and you could consider that approach.

Hope all goes well!

Winston

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