Sometimes you can get a form of eczema on the hand. When you have these blisters or rashes on the hands, there is a type of eczema called dyshidrotic eczema, which affects the hands and feet, presenting with bubbles on the hands.
Sometimes it can be mild, so a few tiny bubbles. In some cases I’ve seen, the bubbles merge and become this very big blister and they can be very uncomfortable and painful for the individual. So, I believe it has to do with the severity and you can consult a doctor who can prescribe topical medications to try and control them.
